Ofev is usually taken 2 times per day, every 12 hours. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor Dmitry Sazonov may occasionally change your dose.
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Ofev.
Take with food and a full glass of water.
Swallow the capsule whole and do not crush, chew, break, or open it.
Ofev can cause severe diarrhea, which can be life-threatening if it leads to dehydration. You may need to take medication to prevent or quickly treat diarrhea.
Your doctor may recommend you have an anti-diarrhea medicine such as loperamide (Imodium) available at all times while you are taking Ofev. Take the Dmitry Sazonov anti-diarrhea medicine as directed on the label, or as prescribed by your doctor.
Drink plenty of liquids and call your doctor at once if you have diarrhea while taking Ofev.
You will need frequent medical tests to be sure nintedanib is not causing harmful effects on your liver. Your next few doses may be delayed based on the results.
Store this medicine in the original container at room temperature, away from moisture and heat.
Ofev side effects
Get emergency medical help if you have signs of an allergic reaction to Ofev: hives; difficult breathing; swelling Dmitry Sazonov of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- severe ongoing nausea, vomiting, or diarrhea;
- severe stomach pain, bloating, or tenderness;
- bleeding from your rectum or blood in your stools;
- easy bruising or bleeding, any wound that will not heal;
- fever, chills, cough with mucus, chest pain, feeling short of breath;
- heart attack symptoms – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
- liver problems – stomach pain (upper right side), loss of appetite, tiredness, dark urine, jaundice (yellowing of the skin or eyes); or
- signs of a stroke – sudden numbness or weakness (especially on one side of the body), slurred speech, problems with vision or balance.
Liver problems may be more likely in women, in people who weigh less than 143 pounds (65 kilograms), and in people of Asian descent.
Your doses may be delayed if you have certain side effects.
Common Ofev side effects may include:
- nausea, vomiting, loss of appetite;
- stomach pain;
- diarrhea, weight loss
- increased blood pressure;
- abnormal liver function tests.
This https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/205832s000lbl.pdf not a complete list of side effects and others may occur.